Factors governing fibrillogenesis of polypeptide chains
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چکیده
Mai Suan Li, Nguyen Truong Co, Govardhan Reddy, C-K. Hu, J. E. Straub, and D. Thirumalai Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, 02-668 Warsaw, Poland Saigon Institute for Computational Science and Technology, 6 Quarter, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam Biophysics Program, Institute for Physical Science and Technology, University of Maryland, College Park, MD 20742 Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742 Institute of Physics, Academia Sinica, Nankang, Taipei 11529, Taiwan Center for Nonlinear and Complex Systems and Department of Physics, Chung Yuan Christian University, Chungli 32023, Taiwan Department of Chemistry, Boston University, Boston, Massachusetts 02215
منابع مشابه
Factors governing fibrillogenesis of polypeptide chains revealed by lattice models.
Using lattice models we explore the factors that determine the tendencies of polypeptide chains to aggregate by exhaustively sampling the sequence and conformational space. The morphologies of the fibril-like structures and the time scales (τ(fib)) for their formation depend on a balance between hydrophobic and Coulomb interactions. The extent of population of an ensemble of N* structures, whic...
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Mai Suan Li, Nguyen Truong Co, Govardhan Reddy, C-K. Hu, and D. Thirumalai Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, 02-668 Warsaw, Poland Saigon Institute for Computational Science and Technology, 6 Quarter, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam Biophysics Program, Institute for Physical Science and Technology, University of Maryland, College ...
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تاریخ انتشار 2010